Signal Transduction Education
Active Learning Projects - Gleevec Project

Groupe 1   Groupe 2   Groupe 3   Groupe 4   Groupe 5   Instructions du Projet

1. Définition générale de la leucémie myeloïde chronique 2. Etiologie et cytogénétique de la leucémie myeloïde chronique 3 Principes généraux de signalisation cellulaire et voies affectées par Bcr-Abl 4. Développement et mode de fonctionnement de Gleevec 5. traitement de la leucémie myeloïde chronique Instructions du Projet

active learning, any time, any place and anywhere

Equipe pédagogique: Sophie North, Sophie Layé, Violaine Moreau et IJsbrand Kramer.

Ce projet est réalisé avec la collaboration de Sophie Corre, ingénieur informatique de l’AMIE (service d’Appui aux Méthodes Innovantes en Enseignement) à l’Université Bordeaux-1.

This website deals with the group-based active learning project, named “Gleevec”, of the Signal Transduction course (BCP608) of Pr IJsbrand Kramer, given to third year biology students at the University of Bordeaux-1. The theme of the projects is “learning through the web, any time any place anywhere”. The projectGleevec has two aims:

1. to learn to translate the knowledge and skills students have acquired during the lecture course, into a richly illustrated and highly informative website that covers a broad spectrum of subjects dealing with cancer and its treatment
2. to make available to society, by means of novel information and communication technology, the fruits of your acquired skills and knowledge.

This signal transduction course is composed of three activities, lectures, practicals and a group based project. With respect to the project, during the 10 weeks of the course the students develop, in groups of four members, a web site in which they describe different aspects of cancer and chronic myelogenous leukaemia in particular and its treatment. This project has been chosen because it demonstrates how an inhibitor of a tyrosine protein kinase (c-Abl) brings transformed blood cells into remission.

Click on the above links to read the project instructions and to read about chronic myelogenous leukemia and its treatment. The content of this website has been verified by staff of the lecture course.