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Signal Transduction Education  
Book Introduction    

Signal Transduction 3rd edition

IJsbrand Kramer, Bastien Gomperts, Peter Tatham

Hardbound, 1045 pages,
Publication date: December 2015
ISBN: 978-0-12-394803-8
Imprint: Academic Press

A reference on cellular signalling processes, the third edition of Signal Transduction continues in the tradition of previous editions, in providing a historical overview of how the concept of stimulus-response coupling arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, growth factors and adhesion molecules. In a new chapter, an introduction to signal transduction, the book provides a concise overview of receptor mechanisms, from receptor –ligand interactions to post-translational modifications operational in the process of bringing about cellular changes. The phosphorylation process, from bacteria to men, is discussed in detail. Signal transduction third edition further elaborates on diverse signalling cascades within particular contexts such as muscle contraction, innate and adaptive immunity, glucose metabolism, regulation of appetite, oncogenic transformation and cell fate decision during development or in stem cell niches. The subjects have been enriched with descriptions of the relevant anatomical, histological, physiological or pathological condition.

Key Features:

  • In-depth insight into a subject central to cell biology and fundamental to biomedicine, including the search for novel therapeutic interventions
  • Essential signalling events embedded in rich physiological and pathological contexts
  • Extensive conceptual colour artwork to assist with comprehension of key topics
  • Special emphasis on how molecular structure determines protein function and subcellular localization
  • Employment of unambiguous protein names (symbols) in agreement withleading protein- and gene databases, allowing the learner to extend his/her exploration on the web

For book contents click here
For more information click here (interactive website available from December 2015 onwards)

Pre-order the book at Elsevier or Amazon or your local bookshop


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